Formulation and Characterization of a Sleeping Mask Gel Utilizing Watermelon (Citrullus lanatus L.) White Rind Juice

Authors

  • Nurain Thomas Universitas Negeri Gorontalo
  • Mohamad Aprianto Paneo Universitas Negeri Gorontalo
  • Putri Rawe Suleman Universitas Negeri Gorontalo

DOI:

https://doi.org/10.70075/jftsk.v2i3.167

Keywords:

Sleeping mask gel, Watermelon white rind juice, HPMC, Physicochemical evaluation, Topical formulation

Abstract

A laboratory-based study was conducted to formulate and evaluate a sleeping-mask gel incorporating juice from the white rind of watermelon (Citrullus lanatus L.) with Hydroxypropyl Methylcellulose (HPMC) as the gelling agent. White-rind juice was prepared and incorporated into gel bases containing 2–5% HPMC with fixed excipients. Characterization encompassed organoleptic properties, homogeneity, pH, adhesion, spreadability, and viscosity according to topical gel quality criteria. Acceptable organoleptic attributes and uniformity were observed for all formulas. pH values (~4.0–6.0) lay within the facial-skin-compatible range. Increasing HPMC concentration was associated with greater adhesion, with minimum criteria satisfied from 4% HPMC. Desired spreadability was obtained at lower-to-intermediate HPMC levels, while viscosity testing indicated that 4–5% HPMC achieved application comfort alongside structural stability. Overall performance identified the 4% HPMC gel as providing the most balanced combination of spreadability, adhesion, and viscosity, yielding a clear and stable preparation. These findings support the feasibility of developing a sleeping-mask gel from watermelon white-rind juice, with a 4% HPMC base recommended as the optimal formulation.

Downloads

Download data is not yet available.

Author Biographies

Nurain Thomas, Universitas Negeri Gorontalo

Department of Pharmacy, Faculty of Sport and Health, Universitas Negeri Gorontalo,  Jenderal Sudirman Street No. 06 Gorontalo City 96128, Indonesia

Mohamad Aprianto Paneo, Universitas Negeri Gorontalo

Department of Pharmacy, Faculty of Sport and Health, Universitas Negeri Gorontalo,  Jenderal Sudirman Street No. 06 Gorontalo City 96128, Indonesia

Putri Rawe Suleman, Universitas Negeri Gorontalo

Department of Pharmacy, Faculty of Sport and Health, Universitas Negeri Gorontalo, Jenderal Sudirman Street No. 06 Gorontalo City 96128, Indonesia

References

Liu JK. Natural products in cosmetics. Nat Products Bioprospect 2022;12. https://doi.org/10.1007/s13659-022-00363-y.

Valle-Vargas MF, Durán-Barón R, Quintero-Gamero G, Valera R. Physicochemical and proximate chemical characterization, bioactive compounds and antioxidant activity from pulp and rind of watermelons (Citrullus lanatus). Inf Tecnol 2020;31:21–8. https://doi.org/10.4067/S0718-07642020000100021.

Afandi N. Natural active ingredients used in topical cosmetic formulations for anti- ageing: A systematic review. Int J Pharm Nutraceuticals Cosmet Sci 2022;5:67–78. https://doi.org/10.24191/ijpnacs.v5i1.05.

Stojiljković D, Pavlović D, Arsić I. Oxidative stress, skin aging and antioxidant therapy. Acta Fac Medicae Naissensis 2014;31:207–17. https://doi.org/10.2478/afmnai-2014-0026.

Bonta M, Daina L. Free Radicals and Antioxidants in the Skin Aging Process 2012:11–20.

Penachin B, Kakuda L, Maia Campos P. Evaluation of the protective and moisturizing effects of cosmetic formulations for the skin containing extracts with film-forming properties. J Biomed Biopharm Res 2022;19:1–18. https://doi.org/10.19277/bbr.19.2.293.

Chiang CF. “Collagen Formula Contained Hydrolyzed Fish Collagen, Pitaya, Rosa Rugosa, and H. Pluvialis, Gamma Aminobutyric Acid Improved Skin and Sleep Condition.” Biomed J Sci Tech Res 2022;47:38182–90. https://doi.org/10.26717/bjstr.2022.47.007455.

Schmitt C, Jacques MC, Andrighetti TT, Antunes AS, Barros CF de, Freitas CMD de, et al. Hydroxypropyl methylcellulose-based films incorporated with Ocimum basilicum L. extract for skin wound healing. Concilium 2022;22:583–97. https://doi.org/10.53660/clm-722-768.

Majee SB, Avlani D, Biswas GR. Hpmc As Capsule Shell Material: Physicochemical, Pharmaceutical and Biopharmaceutical Properties. Int J Pharm Pharm Sci 2017;9:1. https://doi.org/10.22159/ijpps.2017v9i10.20707.

Ardana M, Aeyni V, Ibrahim A. Formulasi dan optimasi basis gel hpmc (. J Trop Pharm Chem 2015;3:101–8.

Sachin Parmar, Amit Gangwal NSD. Scholars Scholars Research Library. Sch Res Libr 2011;2:373–83.

Nofriyanti N-, Wira noviana suhery, Nesa agistia, Wildan khairi muhtadi. Formulasi Dan Evaluasi Fisik Masker Gel Peel Off Ekstrak Kulit Buah Naga Merah (Hylocereus Polyrhizus). J Penelit Farm Indones 2022;11:5–10. https://doi.org/10.51887/jpfi.v11i2.1741.

Maghfirah Rakmadhani, Dwi Rachmawaty, Sesilia Rante Pakadang, Ratnasari Dewi. Formulasi Dan Uji Mutu Fisik Sediaan Masker Gel Peel Off Ekstrak Kulit Buah Pepaya (Carica Papaya L.) Dengan Variasi Konsentrasi Hpmc. J Kefarmasian Akfarindo 2023;8:24–31. https://doi.org/10.37089/jofar.v8i1.196.

Wati E. Formulasi dan Evaluasi Sediaan Masker Gel Peel-Off Sari Buah Mangga Cengkir (Mangifera Indica L.) Sebagai Antioksidan Untuk Menutrisi Kulit Wajah. Parapemikir J Ilm Farm 2022;11:181. https://doi.org/10.30591/pjif.v11i2.2773.

Priani SE, Irawati I, Darma GCE. Formulation of Peel-Off Facial Mask from Mangosteen Pericarp (Garcinia mangostana Linn.). Indones J Pharm Sci Technol 2015;2:90–5. https://doi.org/10.15416/ijpst.v2i3.7905.

Djuwarno EN, Paneo MA. Formulasi Dan Evaluasi Sediaan Facial Scrub Sari Tebu ( Saccharum Officinarum Linn .) Sebagai Exfoliate Cleanser 2025;2:94–102.

Taupik M, Banne PZ, Paneo MA, Puluhulawa LE, Mustapa MA. Formulasi Dan Evaluasi Sediaan Sabun Under Arm Wash Dari Minyak Atsiri Daun Kemangi ( Ocimum sanctum L .) 2025;2:103–11. https://doi.org/10.70075/jftsk.v2i2.190.

Mu A, Suryadi A, Paneo MA, Thomas N, Manno MR, Sabrina PF. Formulasi Dan Evaluasi Sedian Gel Sabun Cuci Tangan Ekstrak Jeruk Kalamansi ( Citrus Microcarpa ). J Farm Teknol Sediaan Dan Kosmet 2025;2:1–15.

Tuloli TS, Pomalango ZB, Paneo MA. Pemanfaatan Rempah Tradisional Kunyit Kawasan Teluk Tomini Sebagai Vitamin Herbal dalam Pencegahan Jantung Pada Masyarakat Pentadu Barat, Kabupaten Boalemo, Provinsi Gorontalo. J Pengabdi Masy Farm Pharmacare Soc 2023;2:140–7. https://doi.org/10.37905/phar.soc.v2i3.21597.

Tungadi R, Thomas NA, Paneo MA, Latif MS, Voenna CD. Formulasi Dan Evaluasi Sediaan Perona Pipi Dalam Bentuk Compact Powder Menggunakan Zar Pewarna Alami Ekstrak Kulit Buah Manggis ( Garcinia Mangostana L .). Indones J Pharm Educ 2024;4:10–7. https://doi.org/10.37311/ijpe.v4i1.18039.

Aprianto Paneo M, Sy Pakaya M, Ain Thomas N, Ratu Cindana Moo F, Efriani Puluhulawa L, Thamrin R, et al. Formulasi Ekstrak Kulit Jeruk Nipis (Citrus Aurantifolia) Dalam Masker Gel Peel-Off Anti Aging Dengan Metode DPPH (2,2-diphenyl-1-picrylhydrazyl). J Farm Teknol Sediaan Dan Kosmet 2024;1:11–20.

Mu A, Suryadi A, Paneo MA, Djuwarno EN, Balikan VA. Formulasi Dan Evaluasi Sediaan Emulgel Sabun Cuci Tangan dari Ekstrak Tomat ( Solanum Lycopersicum L .). J Farm Teknol Sediaan Dan Kosmet 2025;2:45–54.

Pomalango ZB, Paneo MA, Pakaya N, Aman LO, Hutuba AH. Cholesterol-Lowering Effects of Turmeric Effervescent Dosage in Preventing Atherosclerosis 2025;10.

Thomas N, Paneo MA, Mo’o FRC, Puluhulawa LE, Latif MS. Formulation of natural hydrogel from bromelain enzym and alginate-chitosan and the effectiveness test by in vivo in healing burns. J Med Pharm Chem Res 2025;7:944–59. https://doi.org/10.48309/jmpcr.2025.472155.1374.

Tungadi R, Paneo MA, Nurkamiden FS. Pengembangan Teknik Matriks Patch Alpha Arbutin Berbasis Nanoemulsi Dan Uji Permeasi Secara In Vitro 2024;1:53–63.

Herlina Jusuf, Hartono Hadjarati, Mohamad Adam Mustapa, Widy Susanti Abdulkadir, Ahmad M. Andy Suryadi, Muhammad Taupik, et al. Characterization and Formulation of Anti-Aging Cream Using Collagen Derived from Sardine (Sardinella spp.) Fish Scales. Trop J Nat Prod Res 2025;7:3013–20. https://doi.org/10.26538/tjnpr/v9i7.8.

Mustapa MA, Paneo MA, Puluhulawa LE, Latif MS, Nani I. Formulasi Dan Evaluasi Sediaan Exfoliating Gel Sari Buah Anggur ( Vitis vinifera L . ). J Farm Teknol Sediaan Dan Kosmet 2025;2:35–44.

Numberi AM. Uji Stabilitas Fisik Sediaan Masker Gel dari Ekstrak Alga Merah (Poryphyra sp). Maj Farmasetika 2020;5:1–17. https://doi.org/10.24198/mfarmasetika.v5i1.24066.

Jeane HW, Farida D, Hermanu L. Formulasi Ekstrak Kering Kulit Buah Delima ( Punica granatum L .) Sebagai Masker Wajah dalam Bentuk Peel-Off Gel The Formulation of Promegranate Peel Fruit ( Punica granatum L .) in Peel – Off Face Mask Gel. J Pharm Sci an Pract 2020;7:74–80.

Amertyasih KA, Muliadiasa K. Kualitas Selai Kulit Semangka Dengan Penambahan Extrak Bunga Mawar Quality Of Watermelon Skin Jam with The Addition of Rose Flower Extract. J Pariwisata Dan Bisnis) 2023;02:1392–401.

Dewoo MT. Yours Sincerely. Echo Giant 2023:20–20. https://doi.org/10.2307/jj.8784620.23.

Derler S, Gerhardt LC. Tribology of skin: Review and analysis of experimental results for the friction coefficient of human skin. Tribol Lett 2012;45:1–27. https://doi.org/10.1007/s11249-011-9854-y.

Downloads

Published

2025-10-12

How to Cite

Thomas, N., Paneo, M. A., & Suleman, P. R. (2025). Formulation and Characterization of a Sleeping Mask Gel Utilizing Watermelon (Citrullus lanatus L.) White Rind Juice. Jurnal Farmasi Teknologi Sediaan Dan Kosmetika, 2(3), 142–152. https://doi.org/10.70075/jftsk.v2i3.167

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)

<< < 1 2